Histological Typing of Tumours of the Thymus by Juan Rosai MD, Leslie H. Sobin MD (auth.)

By Juan Rosai MD, Leslie H. Sobin MD (auth.)

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The high-power view on the right shows several bizarre tumour cells Fig. 58. Solitary fibrous tumour involving the thymus. Alternation of hyper- and hypocellular foci and the hemangiopericytorna-like areas characterise this entity 54 Fig. 59. Rhabdoid tumour of the thymus. Oval tumour cells with cytoplasmic homogeneous hyaline "inclusions" that displace the nucleus laterally. A residual Hassall corpuscle at right upper corner Fig. 60. True thymic hyperplasia. This thymus weighed 70 g and was excised from a 26-year-old female.

Sharply-outlined areas with a carcinomatous appearance in the upper right alternate with foci having a spindle configuration resulting in a sarcoma-like appearance 40 Fig. 31. Thymic carcinoma, sarcomatoid (carcinosarcoma). In this particular instance, the carcinomatous component of the tumour has a clear cell appearance Fig. 32. Thymic carcinoma, sarcomatoid (carcinosarcoma). High-power view of the sarcomatoid component exhibiting features suggesting skeletal muscle differentiation 41 Fig. 33.

9. Type B1 thymoma. Area of medullary differentiation showing a cluster of epithelial cells at its very centre, possibly representing an abortive attempt at Hassall corpuscle formation Fig. 10. Type B1 thymoma. The predominance of lymphocytes is such as to obscure the thymic epithelial neoplastic component 30 Fig. 11. Type B1 thymoma. A few neoplastic epithelial cells are barely visible in a sea of small lymphocytes Fig. 12. Type B1 thymoma. Another area from the same tumour shown in Fig. II is more easily recognisable as a thymoma because of the occasional clustering of the neoplastic epithelial cells 31 Fig.

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