Glycogen and its Related Enzymes of Metabolism in the by M.Z.M. Ibrahim

By M.Z.M. Ibrahim

Show description

Read or Download Glycogen and its Related Enzymes of Metabolism in the Central Nervous System PDF

Best nonfiction_11 books

Too Different For Comfort

While Lord Salisbury was once requested by means of Queen Victoria to contemplate a reform, he famously responded: "Change? Your majesty, will not be issues undesirable adequate as they're? " in fact, it's within the nature of conservatives to appear askance at switch. yet occasionally, switch is thrust upon us; and in that regard, flip of the century sessions are usually fairly nerve-racking.

Building Evaluation

This ebook is ready development assessment within the broadest experience and it transcends the which means and traditional obstacles of the evolving box of "post-occupancy evalu­ ation" via concentrating on evaluate during the development supply approach. This approach is obvious not only as being linear with a product in brain, i.

Managing Diabetes

Coping with Diabetes is a up to date, accomplished exhibit of the present pharmaceutical traits in treating diabetes and gives a independent, inclusive dialogue of present and rising remedies via famous specialists within the box.

Extra info for Glycogen and its Related Enzymes of Metabolism in the Central Nervous System

Sample text

Neuronal perikarya, processes, astrocytic end-feet, vascular walls and "neuropil" are positive. X 350. (D) Subiculum of hippocampus (grey matter above ) and adjoining alveus (white matter below) show well-localized particulate activity in neurons and diffuse activity in both types of astrocytes, and in "neuropil " . Oligodendrocytic enzyme is not apparent. X 350 32 that the cerebellar molecular layer shows strongest activity; the polyglucose always stained a monochrome brown to purple with iodine indicating its branched nature (see p.

Administration of CNS Depressants It is now well-established that depression of CNS function by hypnosis (Svorad, 1958), or by drugs, induces an increase in its glycogen content provided their effect is maintained for sufficiently long periods; Kerr and Antaki (1937) found no change in rabbit cerebral glycogen when they administered amytal, evipan, ether and chloroform for only 21 / 2-14 min. When some of these anaesthetics were used for 30-60 min there was, however, an increase in cerebral glucosebut not in glycogen-without a concomitant hyperglycaemia; such a response combination, viz.

Among these should be the CNS. Nevertheless, because the lowered blood glucose is overwhelmingly more than the expected increase in glucose uptake, the net result is sometimes a diminution in glucose uptake. Since the glycogen stores of CNS are naturally small they start to be used up, and hence, under such circumstances, the glycogen content of CNS decreases. Proof of such a direct effect of insulin on CNS elements was produced by Prasannan and Subrahmanyam (1965) and by Mellerup and Rafaelson (1969) and Mellerup (1970).

Download PDF sample

Rated 4.21 of 5 – based on 41 votes