Eotaxin 2 by White J.

By White J.

Eotaxin 2 is a CC chemokine that looks to bind solely to the chemokine receptor CCR3. As anticipated, eotaxin 2 acts on cells expressing the CCR3 receptor, together with eosinophils (Sabroe et aL, 1998). basophils (Uguccioni et aL. 1997). TH2 T cells (Gerber et aL, 1997). and sure subsets of dendritic cells (Sato et aL, 1999) to advertise chemotaxis. form switch, and inflammatory mediator creation. Eotaxin 2 is consequently of specific curiosity to researchers learning allergic reaction.

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7, S. 44. 7), im Unterschied zu den Rundproben setzt hier neben der Ausbildung von Quetschzonen die Bildung von Mikrorissen ein, die jedoch im Unterschied zu den Rissen bei Ja = 3 o/oo kurz (l < 30 µm), aber relativ breit sind (Klaffen). 8, S. 47. Die Gleitliniensättigung tritt bei N = 400 ein, ähnlich der Versuche mit Ja = ± 8 0/00 ist keine ausgeprägte Phase der Mikrorissausbreitung zu beobachten. Erst vor dem Versagen, in der Phase des Makrorisswachstums, bilden sich kleine Risse regelmäßig über die Oberfläche.

Die Oberfläche der angrenzenden Körner ist gewölbt, es handelt sich um Quetschzonen infolge hoher Druckverformung. Diese Zonen wachsen nicht über die Größe von einem bis zwei Körnen hinaus. Häufig tritt die Veränderung an den Korngrenzen dreier Körner auf. Neben dem Hauptriss sind keine weiteren Risse nachweisbar. 5). 6, S. 39. Probe 08b versagte bereits bei N = 1600. Die Ursache für das vorzeitige Versagen lag in der frühzeitigen Rissbildung entlang gefalteter Zeilen. Die Zeilen liegen hier nicht parallel, sondern ähneln Gebirgsfaltungen.

Während die Versuche bei Ja = 3 0/00 eine ausgeprägte Phase der Mikrorissbildung und -ausbreitung aufwiesen, wechselten alle Versuche mit Dehnungsamplituden Ja > 5 0/00 von dem Moment der Gleitliniensättigung in die Phase der Makrorissbildung. Oberflächenverwölbung und das Ausbilden von Quetschzonen zeigten sich nur bei Versuchen mit Ja > 5 0/00. Das Ver- und Entfestigungsverhalten unterscheidet sich bei diesen Beanspruchungen ebenfalls. Für Ja = 3 0/00 entfestigt der Werkstoff, während er für Ja > 5 0/00 verfestigt.

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