By Victor Ghetie, Ellen S. Vitetta (auth.), G. E. Francis, Cristina Delgado (eds.)
In Drug focusing on: innovations, equipment, and Protocls, Gillian E. Francis and Cristina Delgado have assembled an exceptional selection of modern protocols for drug concentrating on experiences. as well as supplying unique step by step directions, the hugely skilled authors evaluation the vital present focusing on concepts, talk about find out how to construct the constructs, research theoretical issues suitable to good tumors, and describe experimental and scientific purposes of distinctive drug supply structures. additionally provided are new chemical and organic techniques to the instruction of special biopharmaceuticals, together with ribonuclease-antibody chimeras, bispecific antibodies, enzyme-antibody conjugates, and folate-bearing conjugates. functions contain the concentrating on of myocardial infarctions utilizing liposomal structures, using monoclonal antibodies to focus on malaria and HIV-infected cells, the focusing on of fusion proteins to leukemias and lymphomas, using antioxidant enzyme-antibody conjugates to focus on the pulmonary endothelium, in addition to tools addressing either the lively and passive concentrating on of tumors.
accomplished and leading edge, Drug focusing on: recommendations, equipment, and Protocols records in functional aspect the foremost new chemical and organic concentrating on tools now getting used to supply latest rising wealthy array of novel diagnostic brokers and promising biopharmaceuticals.
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Additional info for Drug Targeting: Strategies, Principles, and Applications
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