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References 1) Waldmann SA, Murad F (1987) Cyclic GMP synthesis and function. Pharmacal Rev 39: 163 - 196 2) Tremblay ), Gerzer R, Hamet P (1988) Cyclic GMP in cell function. Adv Second Messenger Phosphoprotein Res 22: 319 - 383 3) Lincoln TM (1989) Cyclic GMP and mechanisms of vasodilation. Pharmacal Ther 41: 479 - 502 4) Walter U (1989) Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system. Rev Physiol Biochem Pharmacal 113: 41 - 88 5) Kaupp UB (1991) The cyclic nucleotide-gated channels of vertebrate photpreceptors and olfactory epithelium.
1991) Molecular clomng of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase eDNA: identification and distribution of isozyme variants. J. Bioi. Chem. 266: Sept/Oct (in press). • Present address: Department of Pharmacology, University of Texas Southwestern Med. L Garbers Guanylyl cyclase activity is found in both the soluble and particulate fractions of most tissue homogenates. The particulate enzymes can be further divided into those that are easily solubilized and those that are relatively resistant to nonionic detergent solubilization.
Bioi. Chem. 264:13718-13725. 4. A. (1991) High concentrations of a cyclic GMP-stimulated POE mediate ANPinduced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J. Bioi. Chem. 266:136-142. 5. , and ManQaniello, V. C. (1990). clic nucleotide phosphodiesterase from bovine brain: punfication of a distinct cGMP-stimulated isoenzyme. Biochemistry 29: 5285-5292. 6. A. (1991) Molecular clomng of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase eDNA: identification and distribution of isozyme variants.