Ciba Foundation Symposium - Cell Differentiation by A.V.S. & Julie Knight, Editors De Rueck

By A.V.S. & Julie Knight, Editors De Rueck

Chapter 1 Chairman's establishing comments (pages 1–2): Sir Alexander Haddow
Chapter 2 common evaluation of the character of Differentiation (pages 3–17): M. Abercrombie
Chapter three unmarried mobile Properties—Membrane improvement (pages 18–38): Murray D. Rosenberg
Chapter four Biochemical alterations in the course of Fertilization and Early Embryonic improvement (pages 39–64): J. Brachet
Chapter five Nuclear Transplantation and mobile Differentiation (pages 65–78): J. B. Gurdon
Chapter 6 experiences at the suggestions legislation of Haemopoiesis (pages 79–100): Michael Feldman and Ilan Bleiberg
Chapter 7 attainable Mechanisms of the move of knowledge among Small teams of Cells (pages 101–115): E. J. Ambrose
Chapter eight mobile man made actions in Induction of Tissue Transformation (pages 116–130): Tuneo Yamada
Chapter nine the matter of the Chemical Nature of Embryonic Inducers (pages 131–147): Clifford Grobstein
Chapter 10 a few points of the rules of Gene Expression within the Animal phone (pages 148–162): G. P. Georgiev
Chapter eleven keep an eye on of man-made task in the course of improvement (pages 163–177): Eugene Bell and F. Roy MacKintosh
Chapter 12 a few Experiments in terms of the Homogeneity and association of the Ribosomal RNA Genes of Xenopus laevis (pages 178–195): Max Birnstiel
Chapter thirteen covering of Genes in Cytodifferentiation and Carcinogenesis (pages 196–207): John Paul
Chapter 14 elements of progress and upkeep of Tumours as geared up buildings in vitro (pages 208–218): Etienne Wolff and Emilienne Wolff
Chapter 15 The interplay of Tumour and Embryonic Tissue in vivo (pages 219–245): M. E. Whisson
Chapter sixteen Chairman's remaining feedback (pages 246–247): Sir Alexander Haddow

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287-295. FLBISCHER, S. (1964). Sixth Irrterriatiorral Cotgrrss ~ ~ i ~ c ~ f c n ~Abstracts, i s t r y , 604. , and GRENDEL, F. exp. , 41,439-443. , and HECKMAN, K. (1958). J. , 13,266-272. HARKINS, W. , and BOYD,E. (1941). phys. , 45,20-43. HARKINS, W. (1952). The Physical Chetnistry dSuface F i h s . New York: Reinhold. , and LITAN,A. In Molectdur Architecture in Cell Physiology, pp. 3-25, cd. ,and Szcnt-Gyorgyi, A. New Jersey: PrcnticeHall. KAVANAU, J. L. Structure aridFunctiori it1 Biological Membrorrcs,2 vols.

Regarding lipoprotein interactions, there is evidence that phospholipids are essential for the functional integrity of certain enzymes in membranes and that certain membrane-bound enzymes are essential for the formation of phospholipid. Fleischer (1964)~for example, has demonstrated this dependence in the electron transport system of mitochondria. Does this mean that lipoprotein interactions are highly specific ? Dallner, Siekevitz and Palade (19666) argue against this suggestion. They altered the fatty acid composition of the microsomal phospholipids of rat hepatocytes by dietary changes and found no change in phospholipid-dependent enzyme activity.

In Cellular Membratres in Development, pp. 135-173,ed. Locke, M. New York: Academic Press. i DISCUSSION Ambrose: In connexion with the association between phospholipid and protein in cell membranes, in cell-electrophoretic studies which Mr. P. Ward and I made we found that in the EL4 leukaemic cells the outer coating seems to be almost entirely glycoprotein and protein, with sialic acid surface groups. If we treated with pronase, we seemed to be able to peel off this coat almost completely, leaving a practically bare phospholipid coat in which phosphate groups can be detected.

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